By: 8 February 2019
Administering higher doses of oxytocin does not reduce the use of caesarean sections

Delayed labour increases the risk of a caesarean section, even among women who receive oxytocin for augmentation of labour. The rate of caesarean section among first-time mothers is not reduced if the administered dose is doubled either, according to a dissertation from Sahlgrenska Academy at the University of Gothenburg, Sweden.

In her dissertation Lotta Selin, pictured, a midwife, studied data on a total of 2,775 births in Sweden. She has focused on the risk and outcomes of delayed labour and how augmentation of labour with oxytocin is managed.

“Other methods of treatment need to be explored more, such as dosages of oxytocin adapted to specific groups of women and methods applied during labour that can stimulate the body’s own production of the oxytocin hormone,” says Lotta Selin.

Delayed labour is common among first-time mothers, which may lead to a caesarean section and a negative birth experience. In the material studied, the rate of emergency cesarean section among first-time mothers with delayed labour was 17.1 per cent compared with 2.3 per cent for women in the group with a normal progress.

A higher dose of oxytocin, compared with the dose routinely administered today, did not reduce the rate of caesarean section nor did it affect the birth experience. On the other hand, labour was shortened by an average of 23 minutes. No other differences could be demonstrated.

In health care in Sweden, it is common to administer synthetic oxytocin as an intravenous drip for augmentation of labour. According to the dissertation, however, there was substantial overuse and misuse of oxytocin.

“Women whose labour progress was normal also received augmentation with oxytocin to speed up the progress, a treatment that can stimulate excessively frequentuterine contractions, which in turn can cause fetal distress,” Selin points out.

However, when guidelines and controls are carefully followed, i.e. both the woman’s contractions and the baby’s heart sounds are continuously monitored during administration of oxytocin, no adverse effects on the mother and child has been seen.


Source: University of Gothenburg

Reference: Delayed labour – risk factors, use of oxytocin and outcomes;